diff --git a/.circleci/config.yml b/.circleci/config.yml
index fa7691e6..167ae520 100644
--- a/.circleci/config.yml
+++ b/.circleci/config.yml
@@ -60,6 +60,24 @@ jobs:
       - image: circleci/python:3.7
         environment:
           TOXENV: py37-core
+  py38-core:
+    <<: *common
+    docker:
+      - image: circleci/python:3.8
+        environment:
+          TOXENV: py38-core
+  py39-core:
+    <<: *common
+    docker:
+      - image: circleci/python:3.9
+        environment:
+          TOXENV: py39-core
+  py310-core:
+    <<: *common
+    docker:
+      - image: circleci/python:3.10
+        environment:
+          TOXENV: py310-core
   pypy3-core:
     <<: *common
     docker:
diff --git a/setup.py b/setup.py
index 2b8c7201..38e0d78b 100644
--- a/setup.py
+++ b/setup.py
@@ -7,8 +7,8 @@ from setuptools import (
 
 extras_require = {
     'test': [
-        "pytest==5.4.1",
-        "pytest-xdist",
+        "pytest>=6.2.5,<7",
+        "pytest-xdist>=2.4.0,<3",
         "tox==3.14.6",
     ],
     'lint': [
@@ -55,7 +55,7 @@ setup(
     url='https://github.com/ethereum/<REPO_NAME>',
     include_package_data=True,
     install_requires=[
-        "eth-utils>=1,<2",
+        "eth-utils>=2,<3",
     ],
     python_requires='>=3.6, <4',
     extras_require=extras_require,
@@ -75,6 +75,9 @@ setup(
         'Programming Language :: Python :: 3',
         'Programming Language :: Python :: 3.6',
         'Programming Language :: Python :: 3.7',
+        'Programming Language :: Python :: 3.8',
+        'Programming Language :: Python :: 3.9',
+        'Programming Language :: Python :: 3.10',
         'Programming Language :: Python :: Implementation :: PyPy',
     ],
 )
diff --git a/tox.ini b/tox.ini
index 07b2179c..3148e02b 100644
--- a/tox.ini
+++ b/tox.ini
@@ -1,6 +1,6 @@
 [tox]
 envlist=
-    py{36,37,py3}-core
+    py{36,37,38,39,310,py3}-core
     lint
     docs
 
@@ -28,6 +28,9 @@ basepython =
     docs: python
     py36: python3.6
     py37: python3.7
+    py38: python3.8
+    py39: python3.9
+    py310: python3.10
     pypy3: pypy3
 extras=
     test